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Hanna and Doench review the computational methods and tools that have become indispensable for planning and analyzing CRISPR experiments.
Join STAT’s senior infectious diseases and global health reporter, Helen Branswell, for a live video chat with Dr. Frieden, who is now president and CEO of the global public health initiative Resolve to Save Lives. Learn more.
About this question, too, decisions with great consequences are being made, as they must be, based on only glimmers of data.
About this question, too, decisions with great consequences are being made, as they must be, based on only glimmers of data.
Massachusetts grocery store and supermarket workers can now get free coronavirus testing as the state ramps up preparations and activates more National Guard personnel ahead of the “very diff…
China has imposed restrictions on the publication of academic research on the origins of the novel coronavirus, according to a central government directive and online notices published by two Chinese universities, that have since been removed from the web.
Identifying changes in the reproduction number, rate of spread, and doubling time during the course of the COVID-19 outbreak whilst accounting for potential biases due to delays in case reporting both nationally and subnationally in the United States of America. These results are impacted by changes in testing effort, increases and decreases in testing effort will increase and decrease reproduction number estimates respectively (see Methods for further explanation).
Didier Raoult Elsevier has weighed in on the handling of a controversial paper about the utility of hydroxychloroquine to treat Covid-19 infection, defending the rigor of the peer review process fo…
App will send yellow and red alerts to those who have come into contact with a suspected carrier.
The appearance and spread of the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) led to the official declaration of a global pandemic, with states in the US implementing shelter in place orders at an unprecedented scale. SARS-CoV-2 has a robust person-to-person transmission rate and an asymptomatic period of two weeks or more, leading to widespread infection that has overwhelmed healthcare infrastructures around the globe. Effective public health measures require extensive, a...
Experts inside and outside the government identified the threat early on and sought to raise alarms even as President Trump was moving slowly. Read some of what they had to say among themselves at critical moments.
An examination reveals the president was warned about the potential for a pandemic but that internal divisions, lack of planning and his faith in his own instincts led to a halting response.
A report has come out in the NEJM on the experience with "compassionate use" (off-label or not yet approved) of the Gilead drug remdesivir in the Covid-19 epidemic. Here are the inclusion criteria: Patients were those with confirmed SARS-CoV-2 infection who had an oxygen saturation of 94% or less w
People got sick — and some died — after attending crowded parties and theme parks in Florida as the coronavirus spread.
“If people saw this, they would stay home.” What the war against the coronavirus looks like inside two Bronx hospitals.
New York City (NYC) has emerged as one of the epicenters of the current SARS-CoV2 pandemic. To identify the early events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus causing COVID19 in patients seeking care at one of the hospitals of the Mount Sinai Health System. Phylogenetic analysis of 84 distinct SARS-CoV2 genomes indicates multiple, independent but isolated introductions mainly from Europe and other parts of the United States. Moreover, we...
Summary Background There is no specific antiviral therapy recommended for the disease caused by SARS-CoV-2 (COVID-19). Recent publications have drawn attention to the possible benefit of chloroquine (CQ). Our study aimed to comprehensively evaluate the safety and efficacy of two different CQ dosages in patients with established severe COVID-19. Methods We performed a parallel, double-blinded, randomized, phase IIb clinical trial, aiming to assess safety and efficacy of two different CQ dosage...
An infectious-disease expert’s long crusade against some of humanity’s most virulent threats.
UCSF will offer COVID-19 sample analysis for 30 days, free of charge, to all nine Bay Area counties’ Departments of Public Health.
Grein et al. just published a case series of patients with COVID-19 treated with remdesivir via a compassionate use program. I’ve been expecting
Blood samples from healthy volunteers needed to inform public health decision making.
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Deaths from all causes have surged, undermining arguments that coronavirus numbers have been overblown.
Travelers seeded multiple cases starting as early as mid-February, genomes show.
